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Voted NewBeauty's Favorite Serum for Sensitive Skin, 2026 — Shop now →

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Peptide

Acetyl Octapeptide-3

Also known as SNAP-8

A peptide used in anti-aging skincare to help soften the look of expression lines, like those on the forehead and around the eyes.

Revoderm products with Acetyl Octapeptide-3

What is acetyl octapeptide-3?

Acetyl octapeptide-3 is a lab-made peptide, a short chain of amino acids. It's related to acetyl hexapeptide-8 (often called argireline) and is used in skincare to target expression lines, the ones that form where your face moves most.

What it does for your skin

  • Helps soften the look of expression lines on the forehead and around the eyes
  • Complements hydrating and smoothing ingredients in an anti-aging routine

How to use it

Peptides need consistent use, so look for them in products you use every day. Our Detox Facial Cleanser includes acetyl octapeptide-3 along with hyaluronic acid and botanical extracts.

Who it's for

Anyone noticing expression lines who wants a gentle, non-irritating addition to their routine. For deeper lines, ask our clinic team about in-office options.

Common questions

Is acetyl octapeptide-3 like Botox?
It's sometimes compared to it, but a topical peptide works much more gently. It is not a substitute for neuromodulator injections.
How long does it take to see results?
Give peptides 8 to 12 weeks of consistent daily use.

Related ingredients

This guide is general skincare information, not medical advice. If you're pregnant, nursing, using prescription skincare or have a skin condition, check with your doctor or our clinic team first.

Not sure what your skin needs?

Take our skin quiz for a routine matched to your skin, or book a free consult with our skin experts.